MediLytic RF Turbilatex 50 ml

RF Turbilatex is a reagent kit for in-vitro (laboratory) measurement of Rheumatoid Factor (RF) in human serum or plasma.

The “50 ml” refers to the total reagent volume (often packaged as two bottles: a diluent + a latex suspension) for use in semi-automatic or automatic biochemical analyzers.

The test uses the latex turbidimetric method: latex particles coated with human immunoglobulin (IgG) are mixed with the patient serum/plasma sample. 

If RF antibodies are present in the sample, they bind to the IgG on latex particles → this causes agglutination (clumping), which increases turbidity (cloudiness).

The increase in turbidity (absorbance) is measured by the analyzer, and compared against a calibrator of known RF concentration to quantify RF level. 

The main purpose is to aid in diagnosing conditions associated with elevated RF — most notably Rheumatoid Arthritis (RA). 

RF may also be elevated in other autoimmune and rheumatologic disorders (e.g. Systemic Lupus Erythematosus — SLE, Sjogren’s syndrome, etc.) and even in some non-rheumatic conditions.

The kit comes with two reagents (R1 = diluent, R2 = latex suspension) and a calibrator. 

It needs to be stored refrigerated (2-8 °C). 

Sample: human serum or plasma.

For accurate results: avoid hemolyzed, lipemic, or otherwise contaminated samples, and follow the analyzer’s protocol.